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Gastric Lymphoma

According to the American Cancer Society's Non-Hodgkin Lymphoma Overview, gastric lymphoma arises when malignant lymphocytes invade the stomach lining. This expert guide with Dr. Nghia Nguyen at GastroDoxs, Houston, highlights key symptoms, diagnosis, and personalized treatment strategies for improved outcomes.

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Texas Medical Board
Harris County Medical Society
American College of Gastroenterology
American Society for Gastrointestinal Endoscopy
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Houston Methodist leading Medicine
HCA Houston Healthcare
Nghia Nguyen

About the Expert

Dr. Nghia Nguyen, DO, is a board-certified gastroenterologist providing advanced digestive care in the Greater Houston area. He earned his medical degree from the Texas College of Osteopathic Medicine and completed both his Internal Medicine residency and Gastroenterology fellowship at the University of Texas at Rio Grande Valley. Dr. Nguyen specializes in treating conditions such as acid reflux, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and liver disorders.

Common Causes and Risk Factors

  • H. pylori infection (a common stomach bacteria)
  • Chronic stomach inflammation
  • Weakened immune system (e.g., HIV infection or post-transplant)
  • Family history of lymphoma
  • Autoimmune diseases such as lupus or rheumatoid arthritis

Signs and Symptoms

  • Unexplained weight loss
  • Upper abdominal pain or pressure
  • Nausea, vomiting, or persistent heartburn
  • Feeling full quickly when eating
  • Blood in the stool (sometimes hidden)

How Dr. Nghia Nguyen Diagnoses Gastric Lymphoma Presenting with?

Dr. Nguyen uses a step-by-step approach:

Medical History and Physical Exam

He discusses your epigastric pain, weight changes, prior H. pylori infection, autoimmune history, and any family history of lymphoma.

Blood Tests

Complete blood count to check for anemia, H. pylori antibody testing, and basic metabolic panel to assess overall health.

Upper Endoscopy and Biopsy

  • Direct visualization of the stomach lining to identify suspicious lesions.
  • Targeted biopsies of any abnormal areas for histopathological confirmation of lymphoma cells.

Advanced Imaging Studies

  • CT scan of the abdomen and pelvis to evaluate gastric wall thickening and regional lymph node enlargement.
  • PET scan to detect metabolic activity and rule out distant spread.

ICD-10 Coding

Appropriate use of code C83.11 for primary gastric lymphoma ensures accurate records and billing.

Dr. Nghia Nguyen
Treatment

Our Team offers a full range of care for gastric lymphoma.

1. Lifestyle and Supportive Care

  • Regular monitoring (watchful waiting) for indolent lymphoma forms
  • Nutrition counseling to support strength and manage treatment side effects
  • Blood count support with transfusions or growth factors as needed

2. Medications and Systemic Therapies

  • Antibiotic therapy to eradicate H. pylori in early-stage MALT lymphoma
  • Monoclonal antibody immunotherapy (e.g., rituximab)
  • Targeted agents (e.g., BTK or PI3K inhibitors)
  • Combination chemotherapy regimens for aggressive or advanced disease

3. Advanced and Minimally Invasive Procedures

  • Endoscopic resection for localized gastric tumors
  • Focused radiation therapy at tumor sites
  • Stem cell transplant for relapsed or high-risk lymphoma
  • CAR T-cell therapy and clinical trial options
Dr Nghia Nguyen

About the Author

Dr. Nghia Nguyen, DO, is a board-certified gastroenterologist providing advanced digestive care in the Greater Houston area. He earned his medical degree from the Texas College of Osteopathic Medicine and completed both his Internal Medicine residency and Gastroenterology fellowship at the University of Texas at Rio Grande Valley. Dr. Nguyen specializes in treating conditions such as acid reflux, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and liver disorders.

Frequently Asked Questions

What is the survival rate for gastric lymphoma?

It depends on the stage. If caught early, the 5-year survival rate can be over 70%.

How is gastric lymphoma diagnosed?

Only a biopsy taken during an endoscopy can confirm the diagnosis; symptoms alone aren't enough.

Can treating H. pylori cure my lymphoma?

In some early-stage cases, antibiotics against H. pylori can lead to remission.

What does ICD-10 code C83.11 mean?

It's the medical billing code assigned to primary gastric lymphoma.

How long does treatment last?

Treatment duration varies by stage: antibiotics may run for weeks, while chemotherapy can continue for several months.

Will I need surgery?

Not always. Many patients respond well to endoscopic resection or non-invasive therapies.

When should I see a doctor?

If you experience persistent belly pain, unexplained weight loss, or other stomach symptoms lasting more than two weeks, schedule an evaluation.

External Resource American Cancer Society - Non-Hodgkin Lymphoma Overview: https://www.cancer.org/cancer/non-hodgkin-lymphoma.html
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