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Abnormal Results of Liver Function Studies

Liver function tests measure how your liver handles enzymes and proteins such as ALT, AST, ALP, GGT and bilirubin. Abnormal results may indicate underlying issues. At GastroDoxs in Houston, Dr. Nguyen interprets results and offers treatments to restore liver health.

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Texas Medical Board
Harris County Medical Society
American College of Gastroenterology
American Society for Gastrointestinal Endoscopy
Memorial hermann
Houston Methodist leading Medicine
HCA Houston Healthcare
Nghia Nguyen

About the Expert

Dr. Nghia Nguyen, DO, is a board-certified gastroenterologist providing advanced digestive care in the Greater Houston area. He earned his medical degree from the Texas College of Osteopathic Medicine and completed both his Internal Medicine residency and Gastroenterology fellowship at the University of Texas at Rio Grande Valley. Dr. Nguyen specializes in treating conditions such as acid reflux, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and liver disorders.

Common Causes and Risk Factors

  • Non-alcoholic and alcoholic fatty liver disease
  • Viral hepatitis (A, B, C)
  • Certain prescription drugs or herbal supplements
  • Autoimmune liver disorders
  • Gallstones or bile duct obstruction
  • Inherited metabolic conditions (e.g., hemochromatosis)
  • Heavy or long-term alcohol use
  • Obesity, type 2 diabetes, high cholesterol

Signs and Symptoms

  • Often none in early stages
  • Yellowing of the skin or eyes (jaundice)
  • Fatigue, weakness
  • Loss of appetite, nausea
  • Dark urine and pale stools
  • Itchy skin or rashes
  • Pain or fullness in the upper right abdomen

How Dr. Nghia Nguyen Diagnoses Abnormal Liver Function Tests?

Dr. Nguyen uses a systematic, step-by-step approach:

Medical History and Physical Exam

He reviews your symptoms (onset, duration, and character of epigastric pain), alcohol use, medications, family history of liver disease, and lifestyle factors. A focused abdominal exam looks for tenderness, organ enlargement, or signs of chronic liver disease.

Blood Tests

Comprehensive panels include:

  • Liver enzymes (ALT, AST, ALP, GGT) and bilirubin to confirm and quantify liver injury
  • Viral hepatitis markers (A, B, C) and autoimmune antibodies
  • Pancreatic enzymes (amylase, lipase) to evaluate concurrent pancreatic causes of epigastric pain
  • Complete blood count and metabolic profile to assess overall health

Imaging Studies

  • Abdominal ultrasound to assess liver texture, fatty infiltration, and gallbladder or bile duct stones
  • FibroScan (elastography) to measure liver stiffness and fat content non-invasively
  • Cross-sectional imaging (CT or MRI) if anatomic detail or mass evaluation is needed

Advanced Testing (if needed)

If initial tests are inconclusive or suggest advanced disease, Dr. Nguyen may recommend:

  • Liver biopsy to confirm diagnosis, stage fibrosis, and guide therapy
  • MRCP or ERCP to evaluate bile duct obstruction in patients with cholestatic patterns
  • Upper endoscopy to investigate peptic ulcer disease or gastritis contributing to epigastric pain
Dr. Nghia Nguyen
Treatment

Our Team offers a full range of care for fatty liver disease.

1. Lifestyle and Diet Modifications

  • Customized meal plans rich in vegetables, fruits, lean proteins and whole grains
  • Practical guidance to cut down on alcohol, sugar and fried foods
  • Structured exercise recommendations—30 minutes most days—to support gradual weight loss

2. Medications

  • Antiviral therapies when hepatitis is contributing to liver injury
  • Immune-modifying agents for autoimmune liver conditions
  • Pharmacologic support to optimize cholesterol, blood sugar and weight control

3. Minimally Invasive or Advanced Procedures

  • FibroScan or elastography for non-surgical assessment of liver stiffness and fat content
  • Endoscopic procedures (eg, ERCP) to relieve bile duct blockages
  • Image-guided liver biopsy or transjugular biopsy when detailed tissue evaluation is needed
Dr Nghia Nguyen

About the Author

Dr. Nghia Nguyen, DO, is a board-certified gastroenterologist providing advanced digestive care in the Greater Houston area. He earned his medical degree from the Texas College of Osteopathic Medicine and completed both his Internal Medicine residency and Gastroenterology fellowship at the University of Texas at Rio Grande Valley. Dr. Nguyen specializes in treating conditions such as acid reflux, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and liver disorders.

Frequently Asked Questions

What causes a fatty liver?

Fat often collects in the liver from poor diet, obesity, diabetes, alcohol use, or certain medications.

How can I lower my liver enzymes?

Eat a balanced diet, exercise regularly, and avoid excess alcohol. Dr. Pothuri creates a plan to help you lower liver enzymes.

What tests show hepatic echogenicity?

A fatty liver ultrasound or FibroScan measures echogenic liver changes without surgery.

Is there a drug for fatty liver disease?

Yes. We use FDA-approved fatty liver disease drugs when lifestyle changes alone aren't enough.

What is NASH liver disease life expectancy?

It varies by stage. Early NASH can be managed with diet and exercise. Dr. Pothuri will discuss your individual prognosis.

Do I need a biopsy?

Most patients avoid biopsy. We rely on blood tests, imaging, and non-invasive scans unless advanced disease is suspected.

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