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The Link Between Diabetes and Colon Cancer
Not counting skin cancer, colorectal cancer is the third most common form of cancer and the third leading cause of cancer-related deaths in Americans. Colon cancer affects your large intestine, the last stage of the digestive tract.
Welcome to Gastrodoxs.com! Today we’re looking at an important topic: the connection between diabetes and colon cancer.
If you’ve ever asked:
Does diabetes increase colon cancer risk?
How does diabetes affect colon health?
What’s the risk of colon cancer in type 2 diabetics?
You’re in the right place. We’ll explain it all—with help from Houston-based GI expert Dr. Bharat Pothuri.
Section 1: Quick Look at Diabetes
Diabetes happens when your body can’t manage blood sugar properly. There are two main types:
Type 1 – Your body doesn’t make insulin.
Type 2 – Your body doesn’t use insulin well.
Most adults have type 2 diabetes. Over time, high blood sugar can harm organs, nerves, and blood vessels.
“Diabetes isn’t just about sugar,” says Dr. Pothuri. “It affects many parts of the body, including the colon.”
Fast facts:
Over 34 million people in the U.S. have diabetes.
Type 2 is linked to age, weight, and lack of activity.
Early diagnosis helps avoid long-term problems.
Section 2: What Is Colon Cancer?
Colon cancer, also known as colorectal cancer, starts in the large intestine or rectum. It often begins as small growths (polyps) that can turn into cancer over time.
Key points:
Warning signs: blood in stool, changes in bathroom habits, belly pain
Screening tip: colonoscopy every 10 years, or more often if needed
Good news: early detection leads to a 90% five-year survival rate
Slow digestion – Food and waste move more slowly, which may irritate the colon lining.
Unhealthy diets – High-sugar foods hurt more than just blood sugar—they can damage cells.
Weak immune defenses – Poor sugar control makes it harder to fight off abnormal cells.
“In Houston’s hot weather, people struggle to stay on healthy diets,” says Dr. Pothuri. “We help create plans that support both blood sugar and colon health.”
Section 6: Colon Cancer Risk in Type 2 Diabetics
20–30% increased risk of colon cancer
Higher risk for right-sided colon cancer
Men may face slightly more risk than women
The good news? You can lower this risk with the right steps.
Section 7: Dr. Pothuri’s Advice for Patients
“If you have diabetes, don’t skip your screenings,” says Dr. Pothuri.
“We often begin colonoscopies earlier for patients with type 2 diabetes.”
“Healthy weight, good food, regular movement, and stable sugar levels go a long way.”
“Houston has amazing resources—just ask your local Gastrodoxs team for help.”
Section 8: Healthy Habits That Lower Risk
Good habits can protect you from both colon cancer and diabetes problems.
Smart Lifestyle Choices:
Keep a healthy weight
Eat more fiber and less red meat
Exercise at least 150 minutes each week
Avoid smoking and limit alcohol
Keep your blood sugar in check
Screening Musts:
Colonoscopy every 10 years (or every 5 if polyps are found)
Ask your doctor about stool tests
Share your family history with your provider
Tip: The Houston Gastroenterology Center offers walk-in screenings and workshops on sugar control.
Section 9: Risk Comparison Table
Factor
Without Diabetes
With Type 2 Diabetes
Colon Cancer Risk
Baseline
1.2–1.3× higher
Insulin Levels
Normal
High
Inflammation
Low
Chronic
Gut Motility
Normal
Slower
Screening Age
50+
45+ (or earlier if needed)
Section 10: Final Thoughts
Diabetes and colon cancer are connected—but the risks aren’t set in stone.
If you have type 2 diabetes, you may face a higher risk. But with regular screenings, better food choices, exercise, and blood sugar control, you can take charge of your health.
At Gastrodoxs, Dr. Bharat Pothuri and our Houston team are here to help. Let’s build a plan that works for you.
Please share this post with friends and family in Houston and beyond. By learning more about the diabetes and colon cancer connection, we can take steps to stay healthy—together.
About the Author
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.