| Brand Name | Tylenol with Codeine |
| Generic Name | Codeine |
| Drug Class | Mu-Opioid Receptor Agonist |
| Availability | OTC |
| Manufacturer | Various (Generic) |
| Indications | Pain management (moderate to severe) |
| Type | Tablet, Oral Solution |
| Doses | 15-60 mg orally every 4-6 hours |
| Route | Oral |
| Side Effects | Drowsiness, constipation, nausea, dizziness |
| Interactions | Prodrug; metabolism affected by CYP2D6 inhibitors |
| Overdose | Overdose may cause severe digestive symptoms and electrolyte imbalances. |
| Missed Dose | If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. |
| Contraindications | Respiratory depression, MAOI use, head injury. |
| Alternatives | Codeine, Tramadol, Hydrocodone |
| Co-Pay Assistance Program | Available Rx |
| Patient Assistance Program | Not available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Codeine Codeine is an opioid analgesic agent applied in treating mild to moderate pain; in the treatment of a cough that individuals have as a result of a cold or infection.
The working mechanism of codeine is to attach to the opioid receptors on the brain and the spinal cord to make it seem that an individual is not in pain, and to block cough reflexes.
Most frequent side effects are constipation, drowsiness, nausea, and dizziness.
Yes, nestle codeine may be ingested with or without food. Food may lessen stomach upsets.
One should consider taking codeine in pregnancy when the possible benefits are more than risks. Should not be used when you are pregnant.
In case of missed dose, then take it immediately when you decide to do so unless you are about to take your next dose. Do not take two doses at once.
The effects of codeine begin to be felt in 60 to 30 minutes of its administration with the highs being witnessed in 1-2 hours.
Short-term use of codeine is possible in managing short-term pain but care should be monitored in prolonged use of the drug because of the likelihood of dependence and tolerance.
Yes, Codeine is also associated with the relationships with other drugs, in particular, those affecting the central nervous system, including benzodiazepines and alcohol.
In case of life threatening side effects, that is, difficulty breathing or embarrassment, ensure that you do not hesitate or delay action; seek medical attention.
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