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Simponi

Golimumab

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Simponi - Golimumab

Bharat Pothuri Medically Reviewed by Dr. Bharat Pothuri, MD, FACG
Brand Name
Simponi
Generic Name
Golimumab
Drug Class
Anti-TNF-alpha Monoclonal Antibody
Availability
Prescription
Manufacturer
Janssen Biotech (Johnson & Johnson)
Indications
Ulcerative Colitis, Crohn's Disease
Type
Injection
Doses
200 mg (induction) at weeks 0, 2, 4, then 100 mg every 4 weeks for maintenance.
Route
Subcutaneous (SC)
Side Effects
Injection site reactions, upper respiratory infections, fatigue
Interactions
TNF-alpha blocker; similar interaction profile as adalimumab
Overdose
Infection, injection-site reactions.
Missed Dose
Take ASAP or resume on schedule.
Contraindications
Active TB, infections, demyelinating diseases.
Alternatives
Golimumab, Vedolizumab
Co-Pay Assistance Program
Available Rx
Patient Assistance Program
Available

Frequently Asked Questions

What is Golimumab used for?

Golimumab is used to treat autoimmune diseases such as rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis by blocking tumor necrosis factor-alpha (TNF-alpha).

How does Golimumab work?

Golimumab works by binding to TNF-alpha, a protein involved in inflammation, and blocking its action to reduce the inflammatory response in affected tissues.

What are the common side effects of Golimumab?

Common side effects include injection site reactions, upper respiratory infections, and headaches. Serious side effects may include serious infections and liver problems.

How is Golimumab administered?

Golimumab is administered as a subcutaneous injection, typically every four to eight weeks, depending on the specific condition being treated.

Can Golimumab be used for conditions other than rheumatoid arthritis?

Yes, Golimumab is also used to treat psoriatic arthritis and ulcerative colitis, in addition to rheumatoid arthritis.

What should I do if I miss a dose of Golimumab?

If you miss a dose of Golimumab, take it as soon as you remember unless it�s almost time for your next dose. Contact your healthcare provider for guidance.

Is Golimumab safe during pregnancy?

Golimumab should only be used during pregnancy if absolutely necessary. It is important to discuss the risks and benefits with your healthcare provider if you are pregnant or planning to become pregnant.

Can Golimumab cause allergic reactions?

Yes, Golimumab can cause allergic reactions in some people. Seek immediate medical attention if you experience symptoms such as rash, difficulty breathing, or swelling of the face or throat.

How effective is Golimumab in treating psoriatic arthritis?

Golimumab is highly effective in treating psoriatic arthritis, significantly improving symptoms such as joint pain, swelling, and skin lesions in many patients.

Can Golimumab be combined with other medications?

Golimumab may interact with other immunosuppressive medications. Be sure to inform your healthcare provider about any other treatments you are using.