| Brand Name | Humira |
| Generic Name | Adalimumab |
| Drug Class | Anti-TNF-alpha Monoclonal Antibody |
| Availability | Prescription |
| Manufacturer | AbbVie |
| Indications | Ulcerative Colitis, Crohn's Disease |
| Type | Injection |
| Doses | 160 mg (induction), followed by 80 mg at week 2, then 40 mg every other week. |
| Route | Subcutaneous (SC) |
| Side Effects | Injection site reactions, rash, headache, increased risk of infections |
| Interactions | TNF-alpha blocker; increased risk of infections; avoid live vaccines |
| Overdose | Infection risk, fatigue. |
| Missed Dose | Inject ASAP; continue regular schedule. |
| Contraindications | Active infections, TB, hepatitis B, demyelinating disorders. |
| Alternatives | Adalimumab, Golimumab |
| Co-Pay Assistance Program | Available Rx |
| Patient Assistance Program | Available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Adalimumab has been applied in the treatment of various autoimmune disorders, rheumatoid arthritis, psoriatic arthritis, Crohn 125s disease and ulcerative colitis.
Another anti tumor necrosis protein used is Adalimumab that is an anti tumor necrosis factor- alpha (TNF-alpha) which inhibits the process of inflammation thus reducing the inflammation and tissue destruction.
The side effects comprise of headaches, upper respiratory infection and injection site reaction. Other serious side effects can also be serious infections or blood disorders.
Adalimumab is administered locally, injections are normally given in every two weeks depending on the ailment which the drug is enacting and it is also dependent on the sensitivity to the drug.
Adalimumab is also applied in treating Crohn 1/2 disease, psoriasis, ulcerative colitis, ankylosing spondylitis and other autoimmune diseases.
In case you forget to take one of the doses you should take it as soon as you remember regardless unless it is near the other dose. Use as an alternative dose, do not administer two doses simultaneously.
Adalimumab can be administered even in pregnancy in the event that the advantages of administering adalimumab surpass the demerits. This is to be said when you come to your health professional to ensure that you get an idea of this in the event that you are pregnant or you are planning to have a child.
Adalimumab certainly may cause severe infections, e.g. tuberculosis and fungi. It should be monitored and screened when taking treatment.
The effect may not be felt at all and can only be felt after weeks or months particularly in such disease as rheumatoid arthritis and crohn ileum by adaliumab.
Adalimumab can be used with other immunosuppressant drugs or biologic agents. Always keep in mind to tell your medical practitioner about all the drugs that you are taking.
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