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Navoban - Tropisetron

Bharat Pothuri Medically Reviewed by Dr. Bharat Pothuri, MD, FACG
Brand Name
Navoban
Generic Name
Tropisetron
Drug Class
5-HT3 Receptor Antagonist
Availability
Prescription
Manufacturer
Novartis
Indications
Chemotherapy-Induced Nausea and Vomiting
Type
Capsule, Injection
Doses
5 mg IV before chemotherapy, then 5 mg every 12 hours for up to 3 days
Route
IV
Side Effects
Headache, constipation, dizziness
Interactions
May interact with ketoconazole, SSRIs, SNRIs, and QT-prolonging drugs.
Overdose
Headache, dizziness, QT prolongation in rare cases.
Missed Dose
Take ASAP unless close to next dose.
Contraindications
Hypersensitivity, caution in patients with prolonged QT interval
Alternatives
Ondansetron, Granisetron
Co-Pay Assistance Program
Limited availability
Patient Assistance Program
Limited availability

Frequently Asked Questions

What is Tropisetron used for?

Tropisetron is used to prevent nausea and vomiting caused by chemotherapy or radiation therapy, as well as to treat nausea from surgery.

How does Tropisetron work?

Tropisetron works by blocking serotonin receptors in the brain and gastrointestinal tract, which are responsible for triggering nausea and vomiting.

What are the common side effects of Tropisetron?

Common side effects include headache, constipation, and dizziness. Serious side effects may include allergic reactions or heart problems.

How is Tropisetron administered?

Tropisetron is typically administered intravenously (IV) before chemotherapy or radiation treatments to prevent nausea and vomiting.

Is Tropisetron safe during pregnancy?

Tropisetron should only be used during pregnancy if the benefits outweigh the risks. Consult your healthcare provider before using this medication if you are pregnant.

What should I do if I miss a dose of Tropisetron?

If you miss a dose, take it as soon as you remember, unless it�s close to your next scheduled dose. Do not double the dose to make up for a missed one.

Can Tropisetron be used for motion sickness?

Tropisetron is primarily used for chemotherapy-induced nausea and vomiting, not for motion sickness. For motion sickness, consult your healthcare provider for other treatments.

How long does it take for Tropisetron to work?

Tropisetron typically works within a few hours of administration to prevent nausea and vomiting, especially when used before chemotherapy or radiation therapy.

Can Tropisetron cause dizziness?

Yes, dizziness is a common side effect of Tropisetron. If dizziness becomes severe, consult your healthcare provider.

Can Tropisetron interact with other medications?

Tropisetron may interact with other medications, especially those affecting serotonin levels. Always inform your doctor about all medications you're taking.