| Brand Name | De-Nol |
| Generic Name | Bismuth Subcitrate |
| Drug Class | Mucosal Protective Agent |
| Availability | Prescription |
| Manufacturer | Pfizer |
| Indications | Peptic Ulcers, GERD |
| Type | Tablet |
| Doses | 120 mg 4 times daily |
| Route | Oral |
| Side Effects | Darkened stool/tongue, constipation, nausea |
| Interactions | Similar to bismuth subsalicylate; monitor for salicylate toxicity |
| Overdose | Overdose may cause severe digestive symptoms and electrolyte imbalances. |
| Missed Dose | If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. |
| Contraindications | Allergy to bismuth compounds |
| Alternatives | Bismuth Subsalicylate |
| Co-Pay Assistance Program | Available Rx |
| Patient Assistance Program | Not available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
The Bismuth Subcitrate is used in the stomach ulcer like the one caused by the H. pylori and the stomach protection by superseding the effect of the acid.
It functions because Bismuth Subcitrate lathers the ulcer with some protective coating that helps in guarding the ulcer against stomach acid and aids in healing the ulcer.
The side effects include dark colored stool, constipation and light stomach upsets. The side effects are not that numerous and serious and might be allergic in nature.
It should be prescribed on one of them. The long-term side effects that can be realized will be the dark stools or other stomach complications.
Bismuth Subcitrate can be reacting with any other drugs especially the drugs to treat an infection and as such you are supposed to inform your doctor about all your drugs.
Bismuth Subcitrate is not applicable in acid reflux but in acid ulcers, the stomach mucos has been already damaged by acid.
Bismuth Subcitrate should be usually taken as tablets or in the form of liquid prior to sleeping and at the end of the day. Follow the recommendation of your care provider.
Not always does it happen that Bismuth Subcitrate will be recommendable when one is pregnant and here you will always be on the safe side by consulting your doctor before having this.
You should take it there and then in case you forget to take a dose so that you can take the dose then. Do not take two doses at once.
Bismuth Subcitrate is a part of a combination therapy regimen of the H. pylori infections where he is used to both kill the bacteria as well as to prevent the inflammation in the stomach.
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