| Brand Name | Cosentyx |
| Generic Name | Secukinumab |
| Drug Class | Anti-Integrin Monoclonal Antibody |
| Availability | Prescription |
| Manufacturer | Novartis |
| Indications | Ulcerative Colitis, Crohn's Disease |
| Type | Injection |
| Doses | 300 mg at weeks 0, 4, 8, then every 12 weeks for maintenance |
| Route | SC Injection |
| Side Effects | Nasopharyngitis, diarrhea, headache, infections |
| Interactions | IL-17A inhibitor; may increase infection risk |
| Overdose | Severe infections, liver toxicity. |
| Missed Dose | Take ASAP or reschedule if injection missed. |
| Contraindications | Active infections, hypersensitivity, inflammatory bowel disease (IBD) caution. |
| Alternatives | Tofacitinib, Upadacitinib |
| Co-Pay Assistance Program | Not available |
| Patient Assistance Program | Available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Secukinumab is used to treat conditions like moderate to severe plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis by inhibiting interleukin-17A.
Secukinumab works by targeting and inhibiting interleukin-17A, a protein that plays a major role in inflammatory diseases, thereby reducing inflammation and symptoms.
Common side effects include upper respiratory infections, diarrhea, and headache. Serious side effects may include infections or changes in liver function.
Secukinumab is administered as a subcutaneous injection. The frequency of injections may vary depending on your condition and the response to treatment.
Secukinumab is generally considered safe for long-term use, but regular monitoring by a healthcare provider is recommended to check for any potential side effects, especially related to infections.
Secukinumab is primarily used for psoriatic arthritis and ankylosing spondylitis but is not typically used for rheumatoid arthritis. Discuss other options with your doctor if needed.
Secukinumab should be used during pregnancy only if the potential benefits outweigh the risks. Always consult your healthcare provider before using it during pregnancy.
Secukinumab has been shown to be highly effective in treating moderate to severe plaque psoriasis, significantly improving skin lesions and reducing flare-ups.
If you miss a dose, contact your healthcare provider for guidance. Do not take two doses at once unless instructed by your doctor.
Secukinumab may interact with other immunosuppressive medications, so it�s important to inform your healthcare provider about all medications you�re taking.
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