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Anzemet - Dolasetron

Bharat Pothuri Medically Reviewed by Dr. Bharat Pothuri, MD, FACG
Brand Name
Anzemet
Generic Name
Dolasetron
Drug Class
Antiemetic
Availability
Prescription
Manufacturer
Sanofi-Aventis
Indications
Prevention of nausea and vomiting due to chemotherapy or surgery
Type
Tablet, Injection
Doses
100 mg orally, 1.8 mg/kg IV
Route
Oral, Intravenous
Side Effects
Headache, fatigue, dizziness
Interactions
Antiarrhythmic drugs, SSRIs
Overdose
Seek emergency help for severe arrhythmia
Missed Dose
Take as soon as possible unless close to next dose
Contraindications
Hypersensitivity, prolonged QT interval
Alternatives
Ondansetron, Granisetron
Co-Pay Assistance Program
Available
Patient Assistance Program
Available

Frequently Asked Questions

What is Dolasetron used for?

Dolasetron treatments are employed to prevent chemotherapy induced nausea and vomiting and post-surgical nausea and vomiting.

How does Dolasetron work?

The mechanism of action of dolasetron is that it occupies most of the serotonin receptor within the gastrointestinal tract and the brain and this inhibits the signals that cause nausea and vomiting.

What are the side effects that are the most frequent in Dolasetron?

The major side effects are constipation, dizziness, and headache. Arrhythmias (disorders of the heart rhythm) are some of the possible serious side effects.

Common routes of administration Dolasetron How should Dolasetron be given?

Dolasetron is mainly used intravenously (IV) in the clinical setting or orally in the prevention of nausea and vomiting in the aftermath of the chemotherapy or surgery.

Is Dolasetron safe in pregnancy?

The administration of Dolasetron in pregnancy should be performed only when the benefits of this drug exceed the harm. One should talk to their healthcare provider about how to use it.

What happens in case of missing a dose of Dolasetron?

In case you miss a dose, use it immediately after you remember except in case it is nearly the time of your next dose. Do not take two doses at once.

Dolasetron as a motion sickness agent?

Dolasetron is not normally administered to motion sickness. It is mostly applied in the prevention of chemotherapy-induced nausea and vomiting. Other remedies of motion sickness should be checked with your physician.

Dolasetron: There is a delay in its effectiveness.

Dolasetron usually works within a few hours of administration to prevent nausea and vomiting associated with chemotherapy or surgery.

Does Dolasetron have negative cardiac effects?

Yes, dolasetron is capable of interfering with the rhythm of the heart of certain individuals resulting to arrhythmias. This is the reason why cardiac functioning should be monitored during this drug.

Dolasetron Have any interactions with other drugs?

Dolasetron may interact with other drugs especially those used in heart rhythm or serotonin. All of the medications that you take should be informed to your doctor.