| Brand Name | Zeposia |
| Generic Name | Ozanimod |
| Drug Class | JAK Inhibitor |
| Availability | Prescription |
| Manufacturer | Bristol Myers Squibb |
| Indications | Ulcerative Colitis |
| Type | Capsule |
| Doses | Oral: 0.92 mg once daily (induction), 0.92 mg once daily (maintenance) |
| Route | Oral |
| Side Effects | Bradycardia, elevated liver enzymes, infections, headache |
| Interactions | S1P receptor modulator; avoid with immunosuppressants, QT risk |
| Overdose | Bradycardia, immune suppression. |
| Missed Dose | Take ASAP; must restart if missed over 7 days. |
| Contraindications | Severe hepatic impairment, recent MI or stroke |
| Alternatives | Etrasimod, Fingolimod |
| Co-Pay Assistance Program | Available Rx |
| Patient Assistance Program | Available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Ozanimod is also applied in the treatment of multiple sclerosis (MS) and ulcerative colitis; it is an agent that works by relapse.
The mechanism of action of Ozanimod is the modulation of some corpuscles of the white blood cells, which suppresses the biomolecular inflammation and also prevents the broader immune mechanism on the self of the body.
The typical adverse effects will be a headache, high liver enzymes, and infection. Heart complications or acute liver damages can be taken seriously.
Ozanimod is administered orally, often in the form of a capsule daily. Your physician will begin you on a low dose, which he/she will increase.
Ozanimod may have an impact on the heart rate, particularly during their initial therapy. Depending on the first days of treatment, your heart rate can be observed by your doctor.
Ozanimod should never be used during pregnancy since this medication can affect the unborn baby in a negative manner. See your physician in case you feel pregnant or wish to have a baby.
Ozanimod is active in the presence of the ulcerative colitis to decrease the activity of immune cells, which cause inflammation in the colon, thus decreasing the number of flare-ups of the disease.
Which means that, in case you forget about taking the dose of Ozanimod, you may take it immediately but not when it is almost time of your next dose. Do not take two doses at once.
Ozanimod can be subject to interaction with other drugs, in particular, drugs acting on the immune system. You should always inform your medical practitioner of any other medicine that you take.
Ozanimod might not have its full effects on multiple sclerosis and ulcerative colitis in several weeks. Patiently wait and get back to your doctor.
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