| Brand Name | Medrol, Solu-Medrol |
| Generic Name | Methylprednisolone |
| Drug Class | Systemic Corticosteroid |
| Availability | Prescription |
| Manufacturer | Pfizer |
| Indications | Induction of remission in moderate-to-severe IBD |
| Type | Tablet, Injection |
| Doses | 40–60 mg IV daily, taper as symptoms improve |
| Route | IV, Oral |
| Side Effects | GI upset, insomnia, fluid retention, mood changes |
| Interactions | May increase infection risk; interacts with antifungals, vaccines |
| Overdose | GI bleeding, fluid retention, hypertension. |
| Missed Dose | Take ASAP. |
| Contraindications | Systemic fungal infections, live vaccines, untreated infections. |
| Alternatives | Hydrocortisone, Budesonide |
| Co-Pay Assistance Program | Available Rx |
| Patient Assistance Program | Not available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Methylprednisolone is a corticosteroid used to treat inflammation in conditions like arthritis, allergies, and autoimmune disorders.
Methylprednisolone works by suppressing the immune system and reducing inflammation in the body.
Common side effects include insomnia, increased appetite, weight gain, and mood changes.
Yes, Methylprednisolone can be taken with food to reduce the risk of stomach upset.
Methylprednisolone should only be used during pregnancy if the potential benefit justifies the risk to the fetus. Consult your doctor for advice.
If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Do not take two doses at once.
Methylprednisolone usually begins to work within a few hours, with peak effects seen within a day.
Long-term use of Methylprednisolone requires close monitoring by your healthcare provider to avoid serious side effects like high blood pressure and osteoporosis.
If you experience serious side effects such as severe mood changes, swelling, or difficulty breathing, contact your doctor immediately.
Yes, Methylprednisolone can interact with other medications, including blood thinners, insulin, and diuretics. Inform your healthcare provider of all medications you're taking.
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