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Aloxi - Palonosetron

Bharat Pothuri Medically Reviewed by Dr. Bharat Pothuri, MD, FACG
Brand Name
Aloxi
Generic Name
Palonosetron
Drug Class
Antiemetic
Availability
Prescription
Manufacturer
Helsinn Therapeutics
Indications
Prevention of chemotherapy-induced nausea
Type
Injection
Doses
0.25 mg IV
Route
Intravenous
Side Effects
Headache, constipation
Interactions
SSRIs, antipsychotics
Overdose
Contact poison control and seek help
Missed Dose
Administer as soon as possible
Contraindications
Hypersensitivity to palonosetron
Alternatives
Ondansetron, Granisetron
Co-Pay Assistance Program
Available
Patient Assistance Program
Available

Frequently Asked Questions

Which is the Palonosetron application?

Nausea and vomiting that are due to chemotherapy or radiations are prevented by palonosetron.

How does Palonosetron work?

Palonosetron acts by inhibiting serotonin receptors in the brain and in the gastrointestinal tract which are responsible in causing an effect of a nausea and vomiting caused by chemotherapy.

What are the side effects that are prevalent with Palonosetron?

The side effects are commonly constipation, headache and fatigue. Serious side effects can be experienced such as chest pain or irregular heartbeats.

The route of administration of Palonosetron?

Palonosetron is the drug that is usually given by the healthcare provider as an intravenous (IV) infusion, usually just before chemotherapy.

Is Palonosetron safe when pregnant?

Palonosetron can only be applied when absolutely necessary and this is in case of pregnancy. Your medical practitioner should be consulted in the case of being pregnant or conceiving a pregnancy.

Is Palonosetron possible to use as a motion sickness?

Palonosetron is not an effective treatment of motion sickness but rather chemotherapy induced nausea and vomiting. Talk to your medical professional of motion sickness.

What do I do in case I fail to take the dose of Palonosetron?

In case of omitting a dose, take it immediately and before chemotherapy session. In the event that it has been missed but it is near the next time of a regular dose, leave the missed dose behind and resume the dosage.

Is Palonosetron quoted in headaches?

Yes, one of the common side effects of Palonosetron is headaches. In case the headaches are intense or maintaining then consult your healthcare provider.

Interactions Palonosetron can interact with other drugs.

Palonosetron can be combined with other drugs that alter the amount of serotonin. Ensure you always tell your health practitioner concerning all the medications you are taking.

How effective is Palonosetron for preventing nausea from chemotherapy?

Palonosetron is effective in the prevention of nausea and vomiting associated with chemotherapy and radiations with a considerable number of patients reporting a substantial reduction.