| Brand Name | Aloxi |
| Generic Name | Palonosetron |
| Drug Class | Antiemetic |
| Availability | Prescription |
| Manufacturer | Helsinn Therapeutics |
| Indications | Prevention of chemotherapy-induced nausea |
| Type | Injection |
| Doses | 0.25 mg IV |
| Route | Intravenous |
| Side Effects | Headache, constipation |
| Interactions | SSRIs, antipsychotics |
| Overdose | Contact poison control and seek help |
| Missed Dose | Administer as soon as possible |
| Contraindications | Hypersensitivity to palonosetron |
| Alternatives | Ondansetron, Granisetron |
| Co-Pay Assistance Program | Available |
| Patient Assistance Program | Available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Palonosetron is used to prevent nausea and vomiting caused by chemotherapy or radiation therapy.
Palonosetron works by blocking serotonin receptors in the brain and gastrointestinal tract, which helps prevent nausea and vomiting during chemotherapy.
Common side effects include headache, constipation, and fatigue. Serious side effects may include chest pain or irregular heartbeats.
Palonosetron is typically administered as an intravenous (IV) infusion by a healthcare provider, often before chemotherapy sessions.
Palonosetron should only be used during pregnancy if absolutely necessary. Consult your healthcare provider if you are pregnant or planning to become pregnant.
Palonosetron is primarily used for chemotherapy-induced nausea and vomiting, not for motion sickness. Discuss other treatments with your healthcare provider for motion sickness.
If you miss a dose, take it as soon as possible before your chemotherapy session. If it's close to your next dose, skip the missed dose and continue as directed.
Yes, headaches are a common side effect of Palonosetron. If headaches become severe or persistent, consult your healthcare provider.
Palonosetron may interact with other medications that affect serotonin levels. Always inform your healthcare provider about all medications you're taking.
Palonosetron is highly effective in preventing nausea and vomiting caused by chemotherapy and radiation therapy, with many patients experiencing significant relief.
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