Cystic Fibrosis (CF) is a genetically predetermined condition, which occurs as a result of CFTR gene mutation. It brings about the production of the thick sticky mucus which can clog the lungs, the digestive tract and other organs. An estimation of CF occurrence rates in the U.S indicates that about 1 in 3500 babies are born with CF. The current curing has contributed to a massive population of people living the long life-span of about 40 or more years. The CFTR gene blockages also disrupt the protein folding and could lead to amino acid imbalances in the cells.
The CF symptoms are often experienced at an early age. Watch for:
The CF is also an autosomal recessive condition, indicating that the carrier of the disease must possess a defective CFTR gene in each of the parents to transmit CF to the young one. The resultant effects are through these gene mutations:
GastroDoxs is a patient-centred health home of specialists on cystic fibrosis in Houston that aim at offering comprehensive care to their patients including the digestive and breathing components. Developed CFTR modulators and airway clearance therapy to specific-enzyme replacement therapy and special dieting schemes offer the ideal selection of all. You are able to make your appointment and get to breathe better and live a better life today.
Ready to get started? Call us at 832-632-4070 or book your appointment online today.
We've successfully treated more than 1k patients, helping individuals improve their digestive health and overall well-being through expert, personalized care.
With over 20 years of experience, GastroDoxs has been a trusted provider of gastroenterology care, focusing on delivering the best outcomes for patients
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Cystic Fibrosis CF is a hereditary disease that is acquired due to CFTR gene mutations. It leads to development of thick mucus that is sticky and can easily block the digestive tract and lungs that cause respiratory infections that lead to complications in absorbing nutrients.
In America, CF is endemic in one out of every 3500 newborns. It is one of the common genetic diseases that lead to death of individuals of European origin.
As the treatment advanced and the multidisciplinary care was created, currently there are many CF persons who are 40 years or even more. New treatment and care arrangement is improving the life expectation that is based on the individual.
The CFTR gene mutations make the CFTR protein to fold and re-fold in an unnatural manner leading to the improper functioning of the CFTR protein. Misfolds on proteins may disrupt cellular balance of amino acids and ionic transport and the thick mucus and dysfunction of the organ in CF.
CF diagnosis can be performed with the aid of chloride experiment on sweat as the main instrument to identify presence of traces of salt in the sweat and genetic testing to identify mutations in the CFTR gene. Newborn screening programs are used to diagnose CF in many states at an early stage.
Cystic Fibrosis Goodman made possible is caused by two mutated copies of CFTR two copies of the CFTR gene present in each of the parents. The majority aspect of carriers is those that possess one failed gene and at this point with this gene they do not have any symptoms but they can pass the mutation on to their children.
It is managed using CFTR modulators (e.g., ivacaftor, lumacaftor) in normalizing the functioning of the protein, alcoholizing methods of airways and inhaled medicine, secretion inhibition through adding of pancreatic enzymes to food, nutritional management (high calorie content), frequent vaccination.
Yes. Gastroenterologists play a crucial role in the resolution of CF pregnancy related digestive issues of malabsorption, pancreatic insufficiency, liver and nutritional deficiencies. In GastroDoxs, we offer round-the-clock CF attention of our specialists who collaborated with pulmonologists and geneticists.
When the patient or children experience continued coughing or wheezing, frequent lung illness, not gaining weight despite good appetite, greasy stool or have CF in family history, they should turn to the need to consult CF specialist. Early intervention can be used to improve the results.
Appointment to our CF care office in Houston you may do by phone to our office or may book through an online booking site at GastroDoxs. We will have our ownized strategy of action in breathing and leading a better life.
