| Brand Name | Questran, Prevalite |
| Generic Name | Cholestyramine |
| Drug Class | Bile Acid Sequestrant |
| Availability | Prescription |
| Manufacturer | Par Pharmaceutical |
| Indications | Bile acid diarrhea (BAD), IBS-D, chronic diarrhea (post-cholecystectomy) |
| Type | Powder |
| Doses | 4 g 1-6x daily(max 24 g/day) |
| Route | Oral (Powder) |
| Side Effects | Constipation, bloating |
| Interactions | May bind other drugs (warfarin, digoxin) |
| Overdose | May cause severe constipation |
| Missed Dose | May cause severe constipation |
| Contraindications | Biliary obstruction |
| Alternatives | Colesevelam (another bile acid sequestrant) Colestipol (another bile acid sequestrant) Fiber supplements (for bile acid diarrhea management) |
| Co-Pay Assistance Program | Available |
| Patient Assistance Program | Check manufacturer site |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Cholestyramine is used to lower cholesterol levels and treat itching caused by certain types of liver disease by binding bile acids in the intestines.
Cholestyramine works by binding bile acids in the gut, preventing their reabsorption and promoting their excretion, which helps lower cholesterol levels.
Common side effects include constipation, bloating, and indigestion. Long-term use can sometimes lead to nutrient deficiencies due to reduced absorption.
This medication is typically taken in powder form, mixed with water. The dosage and frequency will depend on your doctor�s recommendations and your cholesterol levels.
Cholestyramine is generally considered safe during pregnancy. However, always consult your healthcare provider before starting any medication during pregnancy.
Yes, one of the most common side effects of Cholestyramine is constipation. Drinking plenty of fluids and increasing fiber intake can help manage this side effect.
If you miss a dose, take it as soon as you remember unless it�s almost time for the next dose. Do not take two doses at once.
Yes, Cholestyramine can interfere with the absorption of certain medications, including blood thinners, thyroid medications, and others. Take other medications at least 1 hour before or 4 hours after Cholestyramine.
Cholestyramine may take several weeks to show noticeable effects in lowering cholesterol levels or reducing itching associated with liver disease.
Yes, Cholestyramine can help control diarrhea by binding bile acids in the intestines, particularly in cases of bile acid malabsorption.
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