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Lomotil - Diphenoxylate & Atropine

Bharat Pothuri Medically Reviewed by Dr. Bharat Pothuri, MD, FACG
Brand Name
Lomotil
Generic Name
Diphenoxylate & Atropine
Drug Class
Antidiarrheal
Availability
Prescription
Manufacturer
Pfizer Inc.
Indications
Diarrhea management
Type
Tablet, Liquid
Doses
2 tablets 4 times daily
Route
Oral
Side Effects
Drowsiness, dry mouth
Interactions
CNS depressants, alcohol
Overdose
Seek emergency help for respiratory depression
Missed Dose
Take missed dose as soon as remembered
Contraindications
Severe liver disease, glaucoma
Alternatives
Loperamide
Co-Pay Assistance Program
Available
Patient Assistance Program
Available

Frequently Asked Questions

What is Diphenoxylate & Atropine used for?

This combination medication is used to treat diarrhea by slowing down bowel movements and reducing fluid loss.

How does Diphenoxylate & Atropine work?

Diphenoxylate is an opioid that slows down bowel movements, while Atropine is included to discourage abuse of Diphenoxylate, as it reduces the euphoric effects.

What are the side effects of Diphenoxylate & Atropine?

Common side effects include drowsiness, dizziness, and constipation. Serious side effects may include abdominal distension or allergic reactions.

How should Diphenoxylate & Atropine be taken?

Diphenoxylate & Atropine is typically taken orally as a tablet, with the dosage determined by your healthcare provider based on the severity of your symptoms.

Can Diphenoxylate & Atropine be used for IBS?

Yes, Diphenoxylate & Atropine can be used for diarrhea associated with irritable bowel syndrome (IBS) but should be used under medical supervision.

Is Diphenoxylate & Atropine safe for long-term use?

Diphenoxylate & Atropine is typically used for short-term management of diarrhea. Long-term use should be avoided unless prescribed by a healthcare provider due to potential side effects.

What should I do if I miss a dose of Diphenoxylate & Atropine?

If you miss a dose, take it as soon as you remember unless it�s almost time for your next dose. Do not take two doses at once.

Can Diphenoxylate & Atropine be taken with other medications?

Diphenoxylate & Atropine may interact with other medications, especially those that affect the central nervous system. Inform your healthcare provider of all medications you're taking.

How does Atropine in this combination prevent misuse?

Atropine is included in the combination to discourage misuse, as it causes unpleasant side effects like dry mouth and tachycardia when taken in excess.

Is Diphenoxylate & Atropine safe during pregnancy?

Diphenoxylate & Atropine should be used during pregnancy only if absolutely necessary. Consult your healthcare provider before using it if you are pregnant or planning to become pregnant.