| Brand Name | Lomotil |
| Generic Name | Diphenoxylate & Atropine |
| Drug Class | Antidiarrheal |
| Availability | Prescription |
| Manufacturer | Pfizer Inc. |
| Indications | Diarrhea management |
| Type | Tablet, Liquid |
| Doses | 2 tablets 4 times daily |
| Route | Oral |
| Side Effects | Drowsiness, dry mouth |
| Interactions | CNS depressants, alcohol |
| Overdose | Seek emergency help for respiratory depression |
| Missed Dose | Take missed dose as soon as remembered |
| Contraindications | Severe liver disease, glaucoma |
| Alternatives | Loperamide |
| Co-Pay Assistance Program | Available |
| Patient Assistance Program | Available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
This combination medication is used to treat diarrhea by slowing down bowel movements and reducing fluid loss.
Diphenoxylate is an opioid that slows down bowel movements, while Atropine is included to discourage abuse of Diphenoxylate, as it reduces the euphoric effects.
Common side effects include drowsiness, dizziness, and constipation. Serious side effects may include abdominal distension or allergic reactions.
Diphenoxylate & Atropine is typically taken orally as a tablet, with the dosage determined by your healthcare provider based on the severity of your symptoms.
Yes, Diphenoxylate & Atropine can be used for diarrhea associated with irritable bowel syndrome (IBS) but should be used under medical supervision.
Diphenoxylate & Atropine is typically used for short-term management of diarrhea. Long-term use should be avoided unless prescribed by a healthcare provider due to potential side effects.
If you miss a dose, take it as soon as you remember unless it�s almost time for your next dose. Do not take two doses at once.
Diphenoxylate & Atropine may interact with other medications, especially those that affect the central nervous system. Inform your healthcare provider of all medications you're taking.
Atropine is included in the combination to discourage misuse, as it causes unpleasant side effects like dry mouth and tachycardia when taken in excess.
Diphenoxylate & Atropine should be used during pregnancy only if absolutely necessary. Consult your healthcare provider before using it if you are pregnant or planning to become pregnant.
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