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Eosinophilic Duodenitis

Eosinophilic duodenitis is a rare, immune-mediated condition causing eosinophil accumulation in the duodenum, leading to abdominal pain, nausea, and digestion issues. Dr. Rishi Chadha at GastroDoxs in Houston offers precise diagnosis with endoscopy and tailored treatments for immediate symptom relief.

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Rishi Chadha

About the Expert

Dr. Rishi Chadha, MD is a board‑certified gastroenterologist who specializes in preventive gastroenterology, colorectal cancer screening, and minimally invasive endoscopic procedures. He completed his fellowship at Sunrise Health GME in Las Vegas and previously trained in internal medicine at St. Vincent’s Medical Center in Connecticut.

What Is Eosinophilic Duodenitis?

  • A rare inflammatory condition of the duodenum (first part of the small intestine)
  • Caused by an abnormal buildup of eosinophils (a type of white blood cell)
  • Leads to swelling, pain, and difficulty digesting food

Common Causes and Risk Factors

  • Allergic conditions such as asthma or eczema
  • Food sensitivities or triggers (dairy, wheat, soy, nuts)
  • Family history of allergic or eosinophilic diseases
  • Overactive immune response in the gastrointestinal tract

Common Symptoms

  • Upper abdominal pain or cramping
  • Nausea, vomiting, or acid reflux
  • Loose stools or chronic diarrhea
  • Unintended weight loss
  • Early satiety (feeling full quickly)
  • Bloating or increased abdominal pressure

How Dr. Rishi Chadha Diagnoses Eosinophilic Duodenitis?

Dr. Chadha uses a step-by-step approach:

Symptom Review and Medical History

He evaluates your digestive symptoms, any history of allergies or asthma, and prior treatments to identify potential triggers.

Upper Endoscopy

An endoscope is passed into the small intestine to directly visualize the duodenal lining for signs of irritation or swelling.

Duodenal Biopsy

During endoscopy, small tissue samples are taken from the duodenum to quantify eosinophil levels under the microscope.

Pathology Analysis

Specialized pathologists examine the biopsy for elevated eosinophil counts and other inflammatory cells to confirm the diagnosis.

ICD-10 Coding

Once confirmed, Dr. Chadha documents the condition using code K52.81 for accurate medical records and insurance processing.

Dr. Rishi Chadha
Treatment

Our Houston team offers a full range of care for eosinophilic duodenitis.

1. Lifestyle and Diet Modifications

  • Personalized elimination diets to identify and remove food triggers (dairy, wheat, soy)
  • Gluten-free, dairy-free, or other targeted meal plans
  • Smaller, more frequent meals to ease digestion
  • Soft-fiber foods and tailored hydration strategies to support gut health

2. Medications

  • Proton pump inhibitors (PPIs) to reduce stomach acid and relieve reflux
  • Low-dose budesonide, a locally acting steroid to calm inflammation
  • Antihistamines or mast cell stabilizers to modulate immune responses
  • Targeted nutrition support to restore weight and correct deficiencies

3. Minimally Invasive or Advanced Procedures

  • Endoscopic dilation or therapy for strictures or swollen segments
  • Diagnostic endoscopy with biopsy to monitor eosinophil levels and guide treatment
  • Evaluation of the broader GI tract for concurrent allergic or inflammatory conditions
Rishi Chadha

About the Author

Dr. Rishi Chadha, MD is a board‑certified gastroenterologist who specializes in preventive gastroenterology, colorectal cancer screening, and minimally invasive endoscopic procedures. He completed his fellowship at Sunrise Health GME in Las Vegas and previously trained in internal medicine at St. Vincent’s Medical Center in Connecticut.

Frequently Asked Questions

What is eosinophilic duodenitis?

A condition where eosinophils�a type of white blood cell�build up in the duodenum, causing swelling, pain, and digestive problems.

What causes eosinophilic duodenitis?

It's often triggered by food allergies (dairy, wheat, soy), asthma or other allergic diseases, and an overactive immune response in the gut.

How does Dr. Chadha diagnose it?

He reviews your history and symptoms, performs an upper endoscopy, and takes a duodenal biopsy to count eosinophils in the lab.

What is the ICD-10 code for this condition?

The diagnosis code used for insurance and records is K52.81.

What roles do eosinophils and mast cells play?

They are immune cells that, when overly active in the gut, release substances that irritate and inflame the intestinal lining.

How is eosinophilic duodenitis treated?

Treatment includes elimination diets, PPIs, low-dose budesonide, antihistamines or mast cell stabilizers, and nutrition support.

Will changing my diet really help?

Yes. Removing trigger foods often leads to significant symptom relief within weeks.

Are steroids safe for long-term use?

Dr. Chadha prescribes low-dose budesonide, a topical steroid with fewer systemic side effects than traditional steroids.

How soon can I expect to feel better?

Many patients notice improvement in pain, nausea, and digestion within a few weeks of starting treatment.

How do I schedule a consultation?

Call GastroDoxs in Houston to book your visit with Dr. Rishi Chadha and start your personalized treatment plan.

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