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Rinvoq - Upadacitinib

Bharat Pothuri Medically Reviewed by Dr. Bharat Pothuri, MD, FACG
Brand Name
Rinvoq
Generic Name
Upadacitinib
Drug Class
Janus Kinase 1 (JAK1) Inhibitor
Availability
Prescription
Manufacturer
AbbVie
Indications
Ulcerative Colitis
Type
Tablet
Doses
45 mg once daily
Route
Oral
Side Effects
Upper respiratory infections, acne, nausea, increased cholesterol levels
Interactions
JAK inhibitor; monitor for serious infections, liver enzymes
Overdose
Overdose may lead to increased immunosuppression, risk of serious infections, or cardiovascular effects; immediate medical attention recommended.
Missed Dose
Take ASAP; must monitor first dose.
Contraindications
Severe hepatic impairment, active infection
Alternatives
Tofacitinib, Filgotinib
Co-Pay Assistance Program
Available Rx
Patient Assistance Program
Available

Frequently Asked Questions

What is Upadacitinib used for?

Upadacitinib is used to treat moderate to severe rheumatoid arthritis and other inflammatory conditions by targeting specific immune system pathways.

How does Upadacitinib work?

Upadacitinib works by inhibiting Janus kinases (JAKs), enzymes that play a role in the inflammatory process, thus reducing inflammation and tissue damage.

What are the side effects of Upadacitinib?

Common side effects include upper respiratory infections, headache, and nausea. Serious side effects may include infections, blood clots, or changes in blood counts.

How should Upadacitinib be taken?

Upadacitinib is usually taken as an oral tablet once daily. Your healthcare provider will determine the appropriate dose based on your condition.

Can Upadacitinib be used for other conditions besides rheumatoid arthritis?

Yes, Upadacitinib is also used to treat other inflammatory conditions such as psoriatic arthritis, ulcerative colitis, and atopic dermatitis.

Is Upadacitinib safe during pregnancy?

Upadacitinib is not recommended during pregnancy unless absolutely necessary. Consult your healthcare provider if you are pregnant or planning to become pregnant.

Can Upadacitinib interact with other medications?

Upadacitinib may interact with other medications, including vaccines, blood thinners, and certain antibiotics. Always inform your doctor about any medications you're taking.

What should I do if I miss a dose of Upadacitinib?

If you miss a dose, take it as soon as you remember, unless it�s almost time for the next dose. Do not take two doses at once.

Can Upadacitinib cause weight gain?

Weight gain is not a common side effect of Upadacitinib, but any unusual weight changes should be discussed with your healthcare provider.

How does Upadacitinib help with inflammation?

Upadacitinib reduces inflammation by targeting specific enzymes in the immune system that contribute to inflammatory responses in conditions like rheumatoid arthritis.