| Brand Name | Motilium |
| Generic Name | Domperidone |
| Drug Class | Prokinetic Agent |
| Availability | Prescription |
| Manufacturer | Janssen Pharmaceutical |
| Indications | Gastroparesis |
| Type | Tablet |
| Doses | 10-20 mg orally 3-4 times daily |
| Route | Oral |
| Side Effects | Dry mouth, abdominal cramps, headache, QT prolongation (rare) |
| Interactions | May interact with QT-prolonging agents; CYP3A4 inhibitors |
| Overdose | QT prolongation, dizziness, confusion. |
| Missed Dose | Take ASAP; skip if near next. |
| Contraindications | Prolonged QT, GI bleeding |
| Alternatives | Metoclopramide, Itopride, Prucalopride |
| Co-Pay Assistance Program | Available |
| Patient Assistance Program | Not available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Domperidone is used to treat nausea, vomiting, and gastrointestinal disorders such as gastroparesis by enhancing motility in the stomach and intestines.
Domperidone works by blocking dopamine receptors in the gastrointestinal tract, which helps improve gastric motility and reduce nausea and vomiting.
Common side effects include dry mouth, headache, and dizziness. In rare cases, it can cause more serious side effects like heart problems or involuntary muscle movements.
Domperidone is typically taken orally in tablet form, 15 to 30 minutes before meals. Your doctor will adjust the dosage based on your condition.
Domperidone should be used during pregnancy only if the potential benefits outweigh the risks. Consult your healthcare provider for guidance if you are pregnant.
If you miss a dose, take it as soon as you remember unless it�s almost time for the next dose. Do not take two doses at once.
Yes, Domperidone can cause serious heart issues, such as arrhythmias. Your doctor may monitor your heart function while you're on this medication.
Yes, Domperidone can interact with other medications, particularly those affecting heart rhythm or dopamine levels. Always inform your doctor about all medications you're taking.
Domperidone typically works within an hour of taking it to relieve symptoms of nausea, vomiting, and gastric discomfort.
Domperidone can be used for short-term nausea relief, but long-term use should be monitored by a healthcare provider due to potential side effects.
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