| Brand Name | Mayzent |
| Generic Name | Siponimod |
| Drug Class | Dopamine (D2) Antagonist |
| Availability | Prescription |
| Manufacturer | Novartis |
| Indications | Multiple Sclerosis, Ulcerative Colitis |
| Type | Tablet |
| Doses | Oral: 0.25 mg once daily (maintenance) |
| Route | Oral |
| Side Effects | Headache, high blood pressure, infections, bradycardia |
| Interactions | CYP2C9 and 3A4 interaction; avoid with strong modulators |
| Overdose | Slowed heart rate, infection risk. |
| Missed Dose | Take ASAP unless advised otherwise. |
| Contraindications | Active infections, liver failure, pregnancy (caution). |
| Alternatives | Ozanimod, Etrasimod, Fingolimod |
| Co-Pay Assistance Program | Available Rx |
| Patient Assistance Program | Available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Siponimod is used to treat multiple sclerosis (MS), specifically for relapsing forms of the disease to reduce relapse rates and slow down progression.
Siponimod works by modulating the immune system, reducing the number of immune cells that attack the central nervous system in MS.
Common side effects include headache, high blood pressure, liver enzyme changes, and respiratory infections.
Yes, Siponimod can be taken with or without food.
Siponimod should not be used during pregnancy, as it can harm the fetus. Consult your doctor before using it if you are pregnant or planning to become pregnant.
If you miss a dose, take it as soon as you remember, unless it�s almost time for the next dose. Do not take two doses at once.
Siponimod may take a few weeks to show noticeable effects in reducing relapse rates and slowing the progression of multiple sclerosis.
Siponimod can be used long-term to manage multiple sclerosis, but regular monitoring by a healthcare provider is necessary to manage potential side effects.
Yes, Siponimod can interact with medications like immunosuppressive drugs, certain antifungals, and antidepressants. Inform your doctor about all medications you're taking.
If you experience severe side effects like breathing difficulties or a significant change in heart rate, seek medical attention immediately.
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