| Brand Name | Jyseleca |
| Generic Name | Filgotinib |
| Drug Class | Anti-TL1A Monoclonal Antibody |
| Availability | Prescription |
| Manufacturer | Gilead Sciences |
| Indications | Ulcerative Colitis |
| Type | Tablet |
| Doses | 200 mg daily |
| Route | Oral |
| Side Effects | Nausea, headache, diarrhea, increased infection risk |
| Interactions | JAK1 inhibitor; increased infection risk; monitor CBC |
| Overdose | Increased infection risk, GI symptoms. |
| Missed Dose | Take ASAP. Skip if close to next dose. |
| Contraindications | Severe hepatic impairment, active infection |
| Alternatives | Tofacitinib, Upadacitinib |
| Co-Pay Assistance Program | Available Rx |
| Patient Assistance Program | Available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
The Filgotinib finds its applications in the moderate and severe rheumatoid arthritis and it is subjected to trials with respect to its effectiveness in other inflammatory conditions.
The mechanism of action of Filgotinib that is a significant component of the immune system and the inflammatory process is the selective blockage of Janus kinase 1 (JAK1) and plays a role in the pathogenesis of rheumatoid arthritis.
The most common side effects are the upper respiratory infections, nausea and headache. The side effects may be very severe such as infection, liver related problem or blood clots.
The filgotinib is now given orally in the form of daily dose. The dosage and the length of treatment would depend on your condition and would be decided by your healthcare provider.
In the same fashion, Yes, Filgotinib is equally conducting research on the field of ulcerative colitis and Crohn disease that are the disorders entailing inflammation.
Pregnancy should not be taken in the drug. Another fact you need to consider prior to using this kind of drug is that you would need to consult with your physician as you may also be pregnant or you may also have intentions to deliver another child.
Weight gain is not a prevalent side effect of Filgotinib. Nevertheless, your health care provider should monitor any excessive variation of the weights.
Should you forget to take your dose you should take it until the time that you are near your first dose. Do not take two doses at once.
The use of filgotinib inhibits inflammation and damage caused by rheumatoid arthritis through the use of JAK1 enzymes which is an immune system.
Any other drug can be interacted with filgotinib especially the immune system or acting drugs of the liver. When taking any form of medication, there is always the need of keeping your doctor updated on the type of medication being taken.
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