| Brand Name | Zeposia |
| Generic Name | Ozanimod |
| Drug Class | JAK Inhibitor |
| Availability | Prescription |
| Manufacturer | Bristol Myers Squibb |
| Indications | Ulcerative Colitis |
| Type | Capsule |
| Doses | Oral: 0.92 mg once daily (induction), 0.92 mg once daily (maintenance) |
| Route | Oral |
| Side Effects | Bradycardia, elevated liver enzymes, infections, headache |
| Interactions | S1P receptor modulator; avoid with immunosuppressants, QT risk |
| Overdose | Bradycardia, immune suppression. |
| Missed Dose | Take ASAP; must restart if missed over 7 days. |
| Contraindications | Severe hepatic impairment, recent MI or stroke |
| Alternatives | Etrasimod, Fingolimod |
| Co-Pay Assistance Program | Available Rx |
| Patient Assistance Program | Available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Ozanimod is used to treat relapsing forms of multiple sclerosis (MS) and ulcerative colitis.
Ozanimod works by modulating certain receptors on white blood cells, reducing inflammation and preventing the immune system from attacking the body�s own tissues.
Common side effects include headache, elevated liver enzymes, and infections. Serious effects may include heart problems or severe liver damage.
Ozanimod is taken orally, usually as a capsule once daily. Your doctor will start you on a low dose and gradually increase it.
Ozanimod can affect heart rate, especially when treatment is first started. Your doctor may monitor your heart rate during the first few days of treatment.
Ozanimod is not recommended during pregnancy as it may harm the unborn child. If you are pregnant or planning to become pregnant, consult your doctor.
Ozanimod works by reducing the activity of immune cells that cause inflammation in the colon, helping to reduce flare-ups of ulcerative colitis.
If you miss a dose of Ozanimod, take it as soon as you remember unless it's almost time for the next dose. Do not take two doses at once.
Ozanimod may interact with other medications, especially those that affect the immune system. Always inform your healthcare provider about any other medications you're taking.
It may take several weeks for Ozanimod to show its full effects in treating multiple sclerosis and ulcerative colitis. Be patient and follow up with your doctor as needed.
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