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Zeposia - Ozanimod

Bharat Pothuri Medically Reviewed by Dr. Bharat Pothuri, MD, FACG
Brand Name
Zeposia
Generic Name
Ozanimod
Drug Class
JAK Inhibitor
Availability
Prescription
Manufacturer
Bristol Myers Squibb
Indications
Ulcerative Colitis
Type
Capsule
Doses
Oral: 0.92 mg once daily (induction), 0.92 mg once daily (maintenance)
Route
Oral
Side Effects
Bradycardia, elevated liver enzymes, infections, headache
Interactions
S1P receptor modulator; avoid with immunosuppressants, QT risk
Overdose
Bradycardia, immune suppression.
Missed Dose
Take ASAP; must restart if missed over 7 days.
Contraindications
Severe hepatic impairment, recent MI or stroke
Alternatives
Etrasimod, Fingolimod
Co-Pay Assistance Program
Available Rx
Patient Assistance Program
Available

Frequently Asked Questions

What is Ozanimod used for?

Ozanimod is also applied in the treatment of multiple sclerosis (MS) and ulcerative colitis; it is an agent that works by relapse.

How does Ozanimod work?

The mechanism of action of Ozanimod is the modulation of some corpuscles of the white blood cells, which suppresses the biomolecular inflammation and also prevents the broader immune mechanism on the self of the body.

What side effects are associated with Ozanimod?

The typical adverse effects will be a headache, high liver enzymes, and infection. Heart complications or acute liver damages can be taken seriously.

How should Ozanimod be taken?

Ozanimod is administered orally, often in the form of a capsule daily. Your physician will begin you on a low dose, which he/she will increase.

Is Ozanimod associated with heart issues?

Ozanimod may have an impact on the heart rate, particularly during their initial therapy. Depending on the first days of treatment, your heart rate can be observed by your doctor.

Do you think Ozanimod is pregnancy-safe?

Ozanimod should never be used during pregnancy since this medication can affect the unborn baby in a negative manner. See your physician in case you feel pregnant or wish to have a baby.

What is the effect of using Ozanimod in ulcerative colitis?

Ozanimod is active in the presence of the ulcerative colitis to decrease the activity of immune cells, which cause inflammation in the colon, thus decreasing the number of flare-ups of the disease.

What is the response to the question: What should I do in case I miss a dose of Ozanimod?

Which means that, in case you forget about taking the dose of Ozanimod, you may take it immediately but not when it is almost time of your next dose. Do not take two doses at once.

Is it possible to use Ozanimod concurrently with other drugs?

Ozanimod can be subject to interaction with other drugs, in particular, drugs acting on the immune system. You should always inform your medical practitioner of any other medicine that you take.

What is the Time of action of Ozanimod?

Ozanimod might not have its full effects on multiple sclerosis and ulcerative colitis in several weeks. Patiently wait and get back to your doctor.