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Suboxone

Buprenorphine (with naloxone)

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Suboxone - Buprenorphine (with naloxone)

Bharat Pothuri Medically Reviewed by Dr. Bharat Pothuri, MD, FACG
Brand Name
Suboxone
Generic Name
Buprenorphine (with naloxone)
Drug Class
Mucosal Protective Agent
Availability
Prescription
Manufacturer
Reckitt Benckiser, Various
Indications
Opioid Use Disorder (OUD) treatment
Type
Sublingual Tablet, Film
Doses
2-8 mg sublingually once daily
Route
Oral
Side Effects
Headache, nausea, constipation, dizziness, withdrawal symptoms
Interactions
CNS depression; avoid with alcohol or sedatives
Overdose
Sedation, respiratory suppression.
Missed Dose
Take ASAP unless close to next.
Contraindications
Pregnancy, lactation, children under 18 (limited safety data).
Alternatives
Methadone, Morphine, Naltrexone
Co-Pay Assistance Program
Available Rx
Patient Assistance Program
Available

Frequently Asked Questions

What is the purpose of Buprenorphine (with naloxone)?

Buprenorphine (naloxone) is used in the treatment of opioid dependence, and the abuse assists in managing opioid withdrawal symptoms, and cravings.

Mechanism of action of Buprenorphine (with naloxone)?

Buprenorphine is a partial agonist opioid that reduces the withdrawal symptoms and naloxone prevents the influence of opioids which cause misuse.

What are the side effects usually associated with Buprenorphine (with naloxone)?

The side effects are common, comprising of headache, constipation, nausea, dizziness, and drowsiness.

Is it possible to take Buprenorphine (with naloxone) with meals?

It is fine to use Buprenorphine with or without food (with naloxone). It can be taken orally (under the tongue) as a tablet or as film.

Does Buprenorphine (containing naloxone) cause any harm during pregnancy?

Buprenorphine (along with naloxone) is described as a Category C drug in a pregnant period. Only after the benefits likely to come with it are greater than the risk should it be used. Consult your doctor.

What about an instance that I forget to take my dose of Buprenorphine (with naloxone)?

In case you forget to take a dose, you should take it immediately but not almost at the time of the next dose. Do not take two doses at once.

What is the duration of action of Buprenorphine (with naloxone)?

Additionally, buprenorphine (contained as a mix with naloxone) usually begins to act in 1-2 hours, decreasing the withdrawal and desire to use drugs.

Is there any long-term use of Buprenorphine (with naloxone)?

Yes, Buprenorphine (with naloxone) has a long-term rehabilitation potential and has to be applied as a full-scale effort in treating opioid dependence.

Is there an interaction between Buprenorphine (with naloxone) and other mediators?

Yes, Buprenorphine (along with naloxone) may pose an interaction with other drugs, such as benzodiazepines, antidepressants and other central nervous system depressants.

What is to be done in case of side effects of Buprenorphine (with naloxone)?

In case there are severe side effects such as difficulty breathing, confusion, chest pains, then get help immediately.