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Methadose, Dolophine - Methadone

Bharat Pothuri Medically Reviewed by Dr. Bharat Pothuri, MD, FACG
Generic Name
Methadone
Drug Class
Mu-Opioid Receptor Agonist
Availability
Prescription
Manufacturer
Various (Generic)
Indications
Opioid Use Disorder (OUD) treatment
Type
Tablet, Oral Solution
Doses
20-30 mg orally daily
Route
Oral
Side Effects
Sedation, respiratory depression, QT prolongation, constipation
Interactions
Prolongs QT interval; interacts with CYP3A4 modulators
Overdose
Long QT, respiratory depression.
Missed Dose
Take ASAP.
Contraindications
Respiratory depression, acute asthma, paralytic ileus.
Alternatives
Buprenorphine, Naltrexone, Suboxone
Co-Pay Assistance Program
Available Rx
Patient Assistance Program
Available

Frequently Asked Questions

What is Methadone used for?

Methadone is used to treat opioid addiction and to manage pain in patients with severe pain.

How does Methadone work?

Methadone works by changing the way the brain and nervous system respond to pain and by reducing withdrawal symptoms in people addicted to opioids.

What are the common side effects of Methadone?

Common side effects include drowsiness, constipation, sweating, and nausea.

Can Methadone be taken with food?

Yes, Methadone can be taken with or without food, but it is usually taken as a liquid or tablet.

Is Methadone safe during pregnancy?

Methadone can be used during pregnancy but should be done under strict medical supervision, as it may harm the fetus. Consult your doctor before use.

What should I do if I miss a dose of Methadone?

If you miss a dose, take it as soon as you remember unless it�s close to your next dose. Do not take two doses at once.

How long does it take for Methadone to work?

Methadone typically takes several hours to provide relief from pain or withdrawal symptoms.

Can Methadone be used long-term?

Methadone can be used long-term for opioid addiction treatment and chronic pain management, but it requires careful monitoring to avoid dependence and overdose.

Can Methadone interact with other medications?

Yes, Methadone can interact with other medications, especially other central nervous system depressants, such as benzodiazepines and alcohol.

What should I do if I experience side effects from Methadone?

If you experience severe side effects, such as difficulty breathing or severe drowsiness, seek immediate medical attention.