Balloon Dilation
An endoscopic balloon expands across the narrowing under direct visualization and can be sized in a controlled manner.
Best for: Many short benign strictures, rings, peptic narrowing, and selected EoE-related narrowing
Limitations: May require repeat sessions and carries risks of pain, bleeding, aspiration, and perforation
Takeaway: A standard treatment option when the anatomy is suitable
Wire-Guided Bougie Dilation
A tapered dilator passes over a guidewire to widen a longer segment using longitudinal and radial force.
Best for: Selected simple or complex benign strictures when wire guidance and anatomy support safe passage
Limitations: Requires experience and staged sizing; blind passage should be avoided in complex anatomy
Takeaway: An effective alternative to balloon dilation based on stricture characteristics and operator judgment
Cause-Specific Medical Therapy
PPI therapy treats peptic injury, while EoE needs anti-inflammatory treatment such as PPI, swallowed topical steroid, diet therapy, or biologic care.
Best for: Strictures driven by reflux or eosinophilic inflammation
Limitations: Medication does not immediately open a fixed narrowing and should not replace dilation when obstruction is clinically significant
Takeaway: Essential for reducing continued injury after mechanical widening
Refractory-Stricture Therapy
Steroid injection, incisional therapy, temporary stenting, selected self-dilation, or surgery may be used after repeated recurrence.
Best for: Strictures that cannot maintain adequate swallowing despite repeated appropriate dilation and cause treatment
Limitations: Each option has distinct risks including migration, bleeding, perforation, pain, and need for advanced expertise
Takeaway: Escalate only after anatomy, diagnosis, adherence, and malignancy risk are reassessed