William’s Story: Sigmoid colon cancer presenting with new constipation, progressive straining, anemia, and weight loss
A 63-year-old regional sales trainer looking for an explanation for new progressive constipation, narrow stools, worsening straining, left-sided discomfort, fatigue, and unintentional weight loss
William was a regional sales trainer whose first explanation was normal aging.
The decision changed when stools narrowed, fatigue increased, and weight began to fall. The combination of new progressive constipation, narrow stools, worsening straining, left-sided discomfort, fatigue, and unintentional weight loss required a more specific evaluation.
CBC showed iron-deficiency anemia. CT and diagnostic colonoscopy identified a partially obstructing sigmoid mass, and biopsy confirmed adenocarcinoma; staging defined the treatment sequence.
The final plan used multidisciplinary cancer staging, obstruction-risk management, surgical planning, oncology care, and anemia treatment. Follow-up measured safety, symptom resolution, objective recovery, and the risk of recurrence.
New progression, anemia, and weight loss made this a diagnostic constipation pathway, not a stronger-laxative problem.