How is pancreatic insufficiency tested?
The diagnosis of pancreatic insufficiency is performed with the help of stool tests (fecal elastase), blood tests (to rule out the presence of nutrient deficiencies) and radiographic measurements (CT/ MRI). A direct pancreatic functional test can also be done in a few instances.
How is pancreatic insufficiency treated?
This is treated with pancreatic enzyme replacement therapy (PERT) with every meal, dietary changes (low-fat, high-protein diet) along with supplementation of fat-soluble vitamins A, D, E, and K.
What is the main cause of pancreatic insufficiency?
Chronic pancreatitis is the most frequent one. The other causes are cystic fibrosis, pancreatic cancer or surgery, blockage of the pancreatic ducts, and some autoimmune diseases.
What are the first signs of pancreatic insufficiency?
The symptoms in the beginning are usually bloating, gas, and greasy/ foul smelling stools, which are signs of inefficient fat digestion and malabsorption.
What are enzyme medications for pancreatic insufficiency?
The enzyme drugs are capsules of enzymes (lipase, protease, amylase) of the digestive system. They are served with food to assist into the breakdown of fats, proteins and even carbohydrates.
Can pancreatic insufficiency be cured?
Insufficiency of the pancreas is an incurable disease, but the symptoms are treatable with appropriate enzyme therapy and nutrition, which enables most patients to live well despite the disease.
Will I need to take enzyme supplements forever?
In most cases, yes. The doses of enzymes are changed over the course of time depending on the weight, the diet, and the alleviation of symptoms, although a lifetime treatment is generally needed.
Can children develop pancreatic insufficiency?
Yes. Exocrine pancreatic insufficiency may develop in children, more so in children with cystic fibrosis who usually require enzyme therapy and nutritional supervision.
How does pancreatic insufficiency affect life expectancy?
Pancreatic insufficiency patients can be expected to live a normal life with proper treatment and follow-ups.
Are there side effects from enzyme replacement therapy?
The side effects are limited and they are mild gastrointestinal cramps in case of excess dosage of the enzymes. These symptoms are normally mitigated by varying the dosage.